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News:

  • Marcel Deponte receives the Distinguished Teaching Award 2017 of the TU Kaiserslautern. Click here

  • Robin Schumann has joined the lab as a PhD student. Welcome!

 

    Jobs:

    • M. Sc. positions available: We are currently looking for motivated students who want to start a project in 2018. If you are interested in enzymology, malaria, mitochondria and/or redox biology please contact us.


     

    Publications:

    • Cletus Wezena and the Deponte lab showed in the frame of a collaboration with Gabi Pradel's group that the cytosolic glyoxalases of Plasmodium falciparum are dispensable during asexual blood-stage development (Wezena et al. 2017). This brings the long-lasting question whether the glyoxalase system can be exploited as a drug target to an end.


    • Verena Staudacher showed in the frame of a multidisciplinary collaboration that redox-sensitve GFP2 can be used to analyze the inactivation and enzymatic mechanism of peroxiredoxins in real-time in vivo (Staudacher et al. 2017).


    • Cletus Wezena, Johannes Krafczyk and Verena Staudacher systematically analyzed the susceptibility of Plasmodium falciparum towards redox agents. They discovered an unexpected tolerance regarding hydrogen peroxide and detrimental effects of so-called antioxidants (Wezena et al. 2017).